Efremidis opened in September 2018 in the former IBM building on Ernst-Reuter-Platz in Berlin-Charlottenburg. The gallery is situated on the ground floor—the former data center—of the listed building from the early 1960s. Founded by Stavros Efremidis and Tom Woo, the gallery focuses on carefully curated exhibitions. Efremidis aims to present a forward-thinking and innovative program by engaging in dialogues with Berlin-based and international artists.